Recent Publications

November 4, 2015 Read More →

Adjustment of open-loop settings to improve closed-loop results in type 1 diabetes: a multicenter randomized trial

E. Dassau, S.A. Brown, A. Basu, J.E. Pinsker, Y.C. Kudva, R. Gondhalekar, S. Patek, D. Lv, M. Schiavon, J.B. Lee, C.D. Man, L. Hinshaw, K. Castorino, A. Mallad, V. Dadlani, S.K. McCrady-Spitzer, M. McElwee-Malloy, C.A. Wakeman, W.C. Bevier, P.K. Bradley, B. Kovatchev, C. Cobelli, H.C. Zisser, F.J. Doyle III, “Adjustment of open-loop settings to improve […]

September 3, 2015 Read More →

A Coupled Stochastic Model Explains Differences in Cry Knockout Behavior

J.H. Abel, L.A. Widmer, P.C. St. John, J. Stelling, and F.J. Doyle III, ” A Coupled Stochastic Model Explains Differences in Cry Knockout Behavior.” IEEE Life Sciences Letters, Jun 2015. doi:10.1109/LLS.2015.2439498

July 7, 2015 Read More →

Quantifying Stochastic Noise in Cultured Circadian Reporter Cells.

St John PC, Doyle FJ III. PLoS Comput Biol. 2015 Nov 20;11(11):e1004451. doi: 10.1371/journal.pcbi.1004451.

January 28, 2015 Read More →

Systems biology approach to understanding post-traumatic stress disorder

G.S. Thakur, B.J. Daigle Jr, K.R. Dean, Y. Zhang, M. Rodriguez-Fernandez, R. Hammamieh, R. Yang, M. Jett, J. Palma, L.R. Petzold, F.J. Doyle III, “Systems biology approach to understanding post-traumatic stress disorder,” Molecular bioSystems, Jan 2015. [DOI]

December 2, 2014 Read More →

Amplitude metrics for cellular circadian bioluminescence reporters

P.C. St John, S.R. Taylor, J.H. Abel, F.J. Doyle III, “Amplitude metrics for cellular circadian bioluminescence reporters,” Biophysical Journal, vol. 107, no. 11, pp. 2712-22,Dec 2014. [DOI]

November 1, 2014 Read More →

A Multivariate Ensemble Approach for Identification of Biomarkers: Application to Breast Cancer

GS Thakur, BJ Daigle, LR Petzold, FJ Doyle III. “A Multivariate Ensemble Approach for Identification of Biomarkers: Application to Breast Cancer.” IFAC Proceedings Volumes 47 (3), 809-814.

Posted in: Recent Publications
October 26, 2014 Read More →

Closed-loop artificial pancreas systems: engineering the algorithms

F.J. Doyle III, L. M. Huyett, J. B. Lee, H. C. Zisser, E. Dassau , “Closed- Loop Artificial Pancreas Systems: Engineering the Algorithms,” Diabetes Care, May 2014. [DOI]

September 5, 2014 Read More →

Novel insulin delivery profiles for mixed meals for sensor-augmented pump and closed-loop artificial pancreas therapy for type 1 diabetes mellitus

A. Srinivasan, J.B. Lee, E. Dassau, F.J. Doyle III, “Novel insulin delivery profiles for mixed meals for sensor-augmented pump and closed-loop artificial pancreas therapy for type 1 diabetes mellitus,” Journal of Diabetes Science and Technology, vol. 8, no. 5, pp. 957-68,Sep 2014. [DOI]

July 17, 2014 Read More →

Glucose sensing in the peritoneal space offers faster kinetics than sensing in the subcutaneous space

D.R. Burnett, L.M. Huyett, H.C. Zisser, F.J. Doyle III, B.D. Mensh, “Glucose sensing in the peritoneal space offers faster kinetics than sensing in the subcutaneous space,” Diabetes, vol. 63, no. 7, pp. 2498-505,Jul 2014. [DOI]

January 21, 2014 Read More →

Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock

P.C. St John, T. Hirota, S.A. Kay, F.J. Doyle III, “Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock,” Proceedings of the National Academy of Sciences of the United States of America, Jan 2014. [DOI]