J.H. Abel, K. Meeker, D. Granados-Fuentes, P.C. St. John, T.J. Wang, B.B. Bales, F.J. Doyle III, E.D. Herzog, L.R. Petzold. “Functional network inference of the suprachiasmatic nucleus.” Proceedings of the National Academy of Sciences of the United States of America, 113(16), 2016. doi:10.1073/pnas.1521178113
J.H. Abel, L.A. Widmer, P.C. St. John, J. Stelling, and F.J. Doyle III, ”
A Coupled Stochastic Model Explains Differences in Cry Knockout Behavior.” IEEE Life Sciences Letters, Jun 2015. doi:10.1109/LLS.2015.2439498
G.S. Thakur, B.J. Daigle Jr, K.R. Dean, Y. Zhang, M. Rodriguez-Fernandez, R. Hammamieh, R. Yang, M. Jett, J. Palma, L.R. Petzold, F.J. Doyle III, “Systems biology approach to understanding post-traumatic stress disorder,” Molecular bioSystems, Jan 2015. [DOI]
P.C. St John, S.R. Taylor, J.H. Abel, F.J. Doyle III, “Amplitude metrics for cellular circadian bioluminescence reporters,” Biophysical Journal, vol. 107, no. 11, pp. 2712-22,Dec 2014. [DOI]
P.C. St John, T. Hirota, S.A. Kay, F.J. Doyle III, “Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock,” Proceedings of the National Academy of Sciences of the United States of America, Jan 2014. [DOI]
L.A. Widmer, J. Stelling, F.J. Doyle III, “Note: Parameter-independent bounding of the stochastic Michaelis-Menten steady-state intrinsic noise variance,” The Journal of Chemical Physics, vol. 139, no. 16, pp. 166102, Oct 2013. [DOI]
M. Rodriguez-Fernandez, B. Grosman, T.M. Yuraszeck, B.G. Helwig, L.R. Leon, F.J. Doyle III, M. Wang, “Modeling the Intra- and Extracellular Cytokine Signaling Pathway under Heat Stroke in the Liver,” PLoS ONE, vol. 8, no. 9, pp. e73393, 2013. [DOI]
Y. Q. Wang, F. Nunez, F. J. Doyle III. Statistical analysis of the pulse-coupled synchronization strategy for wireless sensor networks. IEEE Transactions on Signal Processing, In press. [DOI]
Y. Q. Wang, Y. Hori, S. Hara, F. J. Doyle III. Intercellular delay regulates the collective period of repressively coupled gene regulatory oscillator networks. IEEE Transactions on Automatic Control, In press. [DOI]
P.C. St John, F.J. Doyle III, “Estimating confidence intervals in predicted responses for oscillatory biological models,” BMC Systems Biology, vol. 7, no. 1, pp. 71, Jul 2013. [DOI]
See a press release covering our recent publication, Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock:
UC Santa Barbara researchers’ new insight into mammalian circadian rhythms could lead to therapies for certain metabolic disorders like obesity and diabetes – See more at: http://www.news.ucsb.edu/2014/013919/resetting-metabolic-clock#sthash.kbLzwK6r.dpuf
A recent press release highlights our groups work in finding biomarkers of post-traumatic stress disorder (PTSD) in order to improve diagnosis and therapy:
http://dev.news.ucsb.edu/2013/013683/serving-those-who-have-served
A number of news articles were recently published on the results of collaborative work concerning synchrony of mammalian circadian rhythms:
A press release for a recent paper published in collaboration with researchers from UCSD.
Full Citation:
T. Hirota, J. W. Lee, P. C. St. John, M. Sawa, K. Iwaisako, T. Noguchi, P. Y. Pongsawakul, T. Sonntag, D. K. Welsh, D. a Brenner, F. J. Doyle, P. G. Schultz, and S. a Kay, “Identification of Small Molecule Activators of Cryptochrome.,” Science, vol. 337, no. 6098, pp. 1094–1097, Jul. 2012.
