Developing control systems for medical applications poses significant challenges, some of which are unique to this field. Physiological systems involve a multitude of interacting subsystems and networks, with multiple feedforward and feedback loops. The dynamics vary both between different individuals, and within the same individual over time. Measurement and estimation of both inter- and intra-patient […]
Based at Harvard University, the Doyle group is comprised of a diverse group of researchers, coming from backgrounds such as computer science, biology, and chemical engineering. Contact us to inquire about open positions.
A Randomized, Placebo-Controlled Double-Blind Trial of a Closed-Loop Glucagon System for Post-Bariatric Hypoglycemia
C. M. Mulla, S. Zavitsanou, A. J. Laguna Sanz, D. Pober, L. Richardson, P. Walcott, I. Arora, B. Newswanger, M. J. Cummins, S. J. Prestrelski, F. J. Doyle III, E. Dassau, M. E. Patti. The Journal of Clinical Endocrinology & Metabolism, 2019.
Sue A. Brown, Boris P. Kovatchev, Dan Raghinaru, John W. Lum, Bruce A. Buckingham, Yogish C. Kudva, Lori M. Laffel, Carol J. Levy, Jordan E. Pinsker, R. Paul Wadwa, Eyal Dassau, Francis J. Doyle, III, Stacey M. Anderson, Mei Mei Church, Vikash Dadlani, Laya Ekhlaspour, Gregory P. Forlenza, Elvira Isganaitis, David W. Lam, Craig Kollman, and Roy W. Beck for the iDCL Trial Research Group. New England Journal of Medicine, 2019.
Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder
Kelsey R. Dean, Rasha Hammamieh, Synthia H. Mellon, Duna Abu-Amara, Janine D. Flory, Guia Guffanti, Kai Wang, Bernie J. Daigle Jr., Aarti Gaurtam, Inyoul Lee, Ruoting Yang, Lynn M. Almli, F. Saverio Bersani, Nabarun Chakraborty, Duncan Donohue, Kimberly Kerly, Taek-Kyun Kim, Eugene Laska, Min Young Lee, Daniel Lindqvist, Adriana Lori, Liangqun Lu, Burook Misganaw, Seif […]
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