Metabolic Models, in Silico Trials, and Algorithms.
Ali Cinar, Ananda Basu, B Wayne Bequette, Marc D Breton, Bruce Buckingham, Eda Cengiz, Claudio Cobelli, Eyal Dassau, Francis J Doyle, Chiara Fabris, Andrea Facchinetti, Irl Hirsch, Roman Hovorka, Peter G Jacobs, Boris P Kovatchev, Chiara Dalla Man, Laurie Quinn, Jay Skyler.
J Diabetes Sci Technol. 2025 Jul;19(4):895-907. doi: 10.1177/19322968251338300. Epub 2025 Jul 1.
Artificial Pancreas: The First 20 Years.
Francis J Doyle, Boris P Kovatchev.
J Diabetes Sci Technol. 2025 Jul;19(4):875-882. doi: 10.1177/19322968251330920. Epub 2025 Jul 1.
Early Stages of Automated Insulin Delivery.
Howard Zisser, Roman Hovorka, Ananda Basu, Tadej Battelino, Charlotte K Boughton, Marc D Breton, Bruce A Buckingham, Sue A Brown, Daniel R Cherñavvsky, Eyal Dassau, Mark D DeBoer, Francis J Doyle, Laya Ekhlaspour, Chiara Fabris, Gregory P Forlenza, Ahmad Haidar, David C Klonoff, Boris Kovatchev, Aaron J Kowalski, Carol J Levy, Yogish C Kudva, David M Maahs, Moshe Phillip, Eric Renard, Steven J Russell, Viral N Shah, Garry M Steil, R Paul Wadwa, Stuart A Weinzimer.
J Diabetes Sci Technol. 2025 Jul;19(4):908-923. doi: 10.1177/19322968251335685. Epub 2025 Jul 1.
Early Stages of Automated Insulin Delivery.
Howard Zisser, Roman Hovorka, Ananda Basu, Tadej Battelino, Charlotte K Boughton, Marc D Breton, Bruce A Buckingham, Sue A Brown, Daniel R Cherñavvsky, Eyal Dassau, Mark D DeBoer, Francis J Doyle, Laya Ekhlaspour, Chiara Fabris, Gregory P Forlenza, Ahmad Haidar, David C Klonoff, Boris Kovatchev, Aaron J Kowalski, Carol J Levy, Yogish C Kudva, David M Maahs, Moshe Phillip, Eric Renard, Steven J Russell, Viral N Shah, Garry M Steil, R Paul Wadwa, Stuart A Weinzimer.
Diabetes Technol Ther. 2025 Jul;27(S3):S33-S47. doi: 10.1089/dia.2025.18802.hz.
Metabolic Models, in Silico Trials, and Algorithms.
Ali Cinar, Ananda Basu, B Wayne Bequette, Marc D Breton, Bruce Buckingham, Eda Cengiz, Claudio Cobelli, Eyal Dassau, Francis J Doyle, Chiara Fabris, Andrea Facchinetti, Irl Hirsch, Roman Hovorka, Peter G Jacobs, Boris P Kovatchev, Chiara Dalla Man, Laurie Quinn, Jay Skyler.
Diabetes Technol Ther. 2025 Jul;27(S3):S21-S32. doi: 10.1089/dia.2025.18800.ac.
Artificial Pancreas: The First 20 Years.
Francis J Doyle, Boris P Kovatchev.
Diabetes Technol Ther. 2025 Jul;27(S3):S1-S8. doi: 10.1089/dia.2025.0134.
Empirical pharmacodynamic model of phenylephrine and intrathecal bupivacaine for mean arterial pressure prediction in obstetric patients presenting for elective cesarean delivery under spinal anesthesia.
Sherwin C Davoud, Basak Ozaslan, Eleonora M Aiello, Ricardo Kleinlein, Braden Eberhard, Hassan Hassan, Francis J Doyle, Vesela P Kovacheva.
J Clin Monit Comput. 2025 Aug;39(4):775-785. doi: 10.1007/s10877-025-01288-w. Epub 2025 Mar 22.
Personalized Model Identification for Glucose Dynamics From Clinical Data With Incomplete Inputs.
Basak Ozaslan, Eleonora M Aiello, Emilia Fushimi, Francis J Doyle, Eyal Dassau.
IEEE Trans Biomed Eng. 2025 Jun;72(6):2001-2012. doi: 10.1109/TBME.2025.3530711.
Concordance of Blood Glucose and CGM During a Pilot Trial of Automated Insulin Delivery in Type 1 Diabetes Pregnancies.
Ravinder Jeet Kaur, Carol J Levy, Kristin Castorino, Christina M Wood-Wentz, Shafaq R Rizvi, Basak Ozaslan, Grenye O'Malley, Mari Charisse Trinidad, Camilla Levister, Mei Mei Church, Donna Desjardins, Selassie Ogyaadu, Corey Reid, Kent R Bailey, Francis J Doyle, Jordan E Pinsker, Eyal Dassau, Yogish C Kudva.
J Endocr Soc. 2024 Apr 15;8(6):bvae071. doi: 10.1210/jendso/bvae071. eCollection 2024 Apr 6.
The Association Between Diet Quality and Glycemic Outcomes Among People with Type 1 Diabetes.
Melanie B Gillingham, Martin Chase Marak, Michael C Riddell, Peter Calhoun, Robin L Gal, Susana R Patton, Peter G Jacobs, Jessica R Castle, Mark A Clements, Francis J Doyle, Michael R Rickels, Corby K Martin.
Curr Dev Nutr. 2024 Mar 26;8(4):102146. doi: 10.1016/j.cdnut.2024.102146. eCollection 2024 Apr.
Glucose Rate-of-Change and Insulin-on-Board Jointly Weighted Zone Model Predictive Control.
Sunil Deshpande, Francis J Doyle, Eyal Dassau.
IEEE Trans Control Syst Technol. 2023 Sep;31(5):2261-2274. doi: 10.1109/tcst.2023.3291573. Epub 2023 Jul 31.
Associations between daily step count classifications and continuous glucose monitoring metrics in adults with type 1 diabetes: analysis of the Type 1 Diabetes Exercise Initiative (T1DEXI) cohort.
Lauren V Turner, Martin Chase Marak, Robin L Gal, Peter Calhoun, Zoey Li, Peter G Jacobs, Mark A Clements, Corby K Martin, Francis J Doyle, Susana R Patton, Jessica R Castle, Melanie B Gillingham, Roy W Beck, Michael R Rickels, Michael C Riddell, T1DEXI Study Group.
Diabetologia. 2024 Jun;67(6):1009-1022. doi: 10.1007/s00125-024-06127-2. Epub 2024 Mar 19.
Factors Affecting Reproducibility of Change in Glucose During Exercise: Results From the Type 1 Diabetes and EXercise Initiative.
Zoey Li, Peter Calhoun, Michael R Rickels, Robin L Gal, Roy W Beck, Peter G Jacobs, Mark A Clements, Susana R Patton, Jessica R Castle, Corby K Martin, Melanie B Gillingham, Francis J Doyle, Michael C Riddell.
J Diabetes Sci Technol. 2025 Jul;19(4):958-970. doi: 10.1177/19322968241234687. Epub 2024 Mar 8.
Effect of Impaired Awareness of Hypoglycemia on Glucose Decline During and After Exercise in the T1DEXI Study.
Jorge L Jo Kamimoto, Zoey Li, Robin L Gal, Jessica R Castle, Francis J Doyle, Peter G Jacobs, Corby K Martin, Roy W Beck, Peter Calhoun, Michael C Riddell, Michael R Rickels.
J Clin Endocrinol Metab. 2024 Aug 13;109(9):2233-2241. doi: 10.1210/clinem/dgae115.
Online Classification of Unstructured Free-Living Exercise Sessions in People with Type 1 Diabetes.
Emilia Fushimi, Eleonora M Aiello, Sunghyun Cho, Michael C Riddell, Robin L Gal, Corby K Martin, Susana R Patton, Michael R Rickels, Francis J Doyle.
Diabetes Technol Ther. 2024 Oct;26(10):709-719. doi: 10.1089/dia.2023.0528. Epub 2024 May 24.
An Anticipatory Scheme for the Model Predictive Control of Circadian Phase for Expected Environmental Light Changes.
Lindsey S Brown, Elizabeth B Klerman, Francis J Doyle.
IEEE Control Syst Lett. 2022;6:1616-1621. doi: 10.1109/LCSYS.2021.3129475. Epub 2021 Nov 22.
Circulating cell-free mitochondrial DNA levels and glucocorticoid sensitivity in a cohort of male veterans with and without combat-related PTSD.
Zachary N Blalock, Gwyneth W Y Wu, Daniel Lindqvist, Caroline Trumpff, Janine D Flory, Jue Lin, Victor I Reus, Ryan Rampersaud, Rasha Hammamieh, Aarti Gautam, SBPBC, Francis J Doyle, Charles R Marmar, Marti Jett, Rachel Yehuda, Owen M Wolkowitz, Synthia H Mellon.
Transl Psychiatry. 2024 Jan 10;14(1):22. doi: 10.1038/s41398-023-02721-x.
Ketone-Based Alert System for Insulin Pump Failures.
Eleonora M Aiello, Lori M Laffel, Mary-Elizabeth Patti, Francis J Doyle.
J Diabetes Sci Technol. 2025 May;19(3):683-691. doi: 10.1177/19322968231209339. Epub 2023 Nov 9.
Artificial Intelligence and Machine Learning for Improving Glycemic Control in Diabetes: Best Practices, Pitfalls, and Opportunities.
Peter G Jacobs, Pau Herrero, Andrea Facchinetti, Josep Vehi, Boris Kovatchev, Marc D Breton, Ali Cinar, Konstantina S Nikita, Francis J Doyle, Jorge Bondia, Tadej Battelino, Jessica R Castle, Konstantia Zarkogianni, Rahul Narayan, Clara Mosquera-Lopez.
IEEE Rev Biomed Eng. 2024;17:19-41. doi: 10.1109/RBME.2023.3331297. Epub 2024 Jan 12.
Pharmacokinetic Model-Based Control across the Blood-Brain Barrier for Circadian Entrainment.
Síofra Ó Murdoch, Eleonora M Aiello, Francis J Doyle.
Int J Mol Sci. 2023 Oct 2;24(19):14830. doi: 10.3390/ijms241914830.
Correction to "Microneedle Aptamer-Based Sensors for Continuous, Real-Time Therapeutic Drug Monitoring".
Yao Wu, Farshad Tehrani, Hazhir Teymourian, John Mack, Alexander Shaver, Maria Reynoso, Jonathan Kavner, Nickey Huang, Allison Furmidge, Andrés Duvvuri, Yuhang Nie, Lori M Laffel, Francis J Doyle, Mary-Elizabeth Patti, Eyal Dassau, Joseph Wang, Netzahualcóyotl Arroyo-Currás.
Anal Chem. 2023 Oct 3;95(39):14830-14831. doi: 10.1021/acs.analchem.3c04237. Epub 2023 Sep 21.
Integrated analysis of proteomics, epigenomics and metabolomics data revealed divergent pathway activation patterns in the recent versus chronic post-traumatic stress disorder.
Seid Muhie, Aarti Gautam, Burook Misganaw, Ruoting Yang, Synthia H Mellon, Allison Hoke, Janine Flory, Bernie Daigle, Kevin Swift, PTSD Systems Biology Consortium, Leroy Hood, Francis J Doyle, Owen M Wolkowitz, Charles R Marmar, Kerry Ressler, Rachel Yehuda, Rasha Hammamieh, Marti Jett.
Brain Behav Immun. 2023 Oct;113:303-316. doi: 10.1016/j.bbi.2023.07.015. Epub 2023 Jul 27.
The Type 1 Diabetes and EXercise Initiative: Predicting Hypoglycemia Risk During Exercise for Participants with Type 1 Diabetes Using Repeated Measures Random Forest.
Simon Bergford, Michael C Riddell, Peter G Jacobs, Zoey Li, Robin L Gal, Mark A Clements, Francis J Doyle, Corby K Martin, Susana R Patton, Jessica R Castle, Melanie B Gillingham, Roy W Beck, Michael R Rickels, Peter Calhoun.
Diabetes Technol Ther. 2023 Sep;25(9):602-611. doi: 10.1089/dia.2023.0140. Epub 2023 Jun 20.
At-Home Use of a Pregnancy-Specific Zone-MPC Closed-Loop System for Pregnancies Complicated by Type 1 Diabetes: A Single-Arm, Observational Multicenter Study.
Carol J Levy, Yogish C Kudva, Basak Ozaslan, Kristin Castorino, Grenye O'Malley, Ravinder Jeet Kaur, Camilla M Levister, Mei Mei Church, Donna Desjardins, Shelly McCrady-Spitzer, Selassie Ogyaadu, Mari Charisse Trinidad, Corey Reid, Shafaq Rizvi, Sunil Deshpande, Isabella Zaniletti, Walter K Kremers, Jordan E Pinsker, Francis J Doyle, Eyal Dassau, LOIS-P Diabetes and Pregnancy Consortium.
Diabetes Care. 2023 Jul 1;46(7):1425-1431. doi: 10.2337/dc23-0173.
Molecular signatures of post-traumatic stress disorder in war-zone-exposed veteran and active-duty soldiers.
Seid Muhie, Aarti Gautam, Ruoting Yang, Burook Misganaw, Bernie J Daigle, Synthia H Mellon, Janine D Flory, Duna Abu-Amara, Inyoul Lee, Kai Wang, Ryan Rampersaud, PTSD Systems Biology Consortium, Leroy Hood, Rachel Yehuda, Charles R Marmar, Owen M Wolkowitz, Kerry J Ressler, Francis J Doyle, Rasha Hammamieh, Marti Jett.
Cell Rep Med. 2023 May 16;4(5):101045. doi: 10.1016/j.xcrm.2023.101045.
Design of a Real-Time Physical Activity Detection and Classification Framework for Individuals With Type 1 Diabetes.
Sunghyun Cho, Eleonora M Aiello, Basak Ozaslan, Michael C Riddell, Peter Calhoun, Robin L Gal, Francis J Doyle.
J Diabetes Sci Technol. 2024 Sep;18(5):1146-1156. doi: 10.1177/19322968231153896. Epub 2023 Feb 17.
Examining the Acute Glycemic Effects of Different Types of Structured Exercise Sessions in Type 1 Diabetes in a Real-World Setting: The Type 1 Diabetes and Exercise Initiative (T1DEXI).
Michael C Riddell, Zoey Li, Robin L Gal, Peter Calhoun, Peter G Jacobs, Mark A Clements, Corby K Martin, Francis J Doyle Iii, Susana R Patton, Jessica R Castle, Melanie B Gillingham, Roy W Beck, Michael R Rickels, T1DEXI Study Group.
Diabetes Care. 2023 Apr 1;46(4):704-713. doi: 10.2337/dc22-1721.
The Genetic Basis for the Increased Prevalence of Metabolic Syndrome among Post-Traumatic Stress Disorder Patients.
Burook Misganaw, Ruoting Yang, Aarti Gautam, Seid Muhie, Synthia H Mellon, Owen M Wolkowitz, Kerry J Ressler, Francis J Doyle, Charles R Marmar, Marti Jett, Rasha Hammamieh.
Int J Mol Sci. 2022 Oct 19;23(20):12504. doi: 10.3390/ijms232012504.
Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice.
Moshe Phillip, Revital Nimri, Richard M Bergenstal, Katharine Barnard-Kelly, Thomas Danne, Roman Hovorka, Boris P Kovatchev, Laurel H Messer, Christopher G Parkin, Louise Ambler-Osborn, Stephanie A Amiel, Lia Bally, Roy W Beck, Sarah Biester, Torben Biester, Julia E Blanchette, Emanuele Bosi, Charlotte K Boughton, Marc D Breton, Sue A Brown, Bruce A Buckingham, Albert Cai, Anders L Carlson, Jessica R Castle, Pratik Choudhary, Kelly L Close, Claudio Cobelli, Amy B Criego, Elizabeth Davis, Carine de Beaufort, Martin I de Bock, Daniel J DeSalvo, J Hans DeVries, Klemen Dovc, Francis J Doyle, Laya Ekhlaspour, Naama Fisch Shvalb, Gregory P Forlenza, Geraldine Gallen, Satish K Garg, Dana C Gershenoff, Linda A Gonder-Frederick, Ahmad Haidar, Sara Hartnell, Lutz Heinemann, Simon Heller, Irl B Hirsch, Korey K Hood, Diana Isaacs, David C Klonoff, Olga Kordonouri, Aaron Kowalski, Lori Laffel, Julia Lawton, Rayhan A Lal, Lalantha Leelarathna, David M Maahs, Helen R Murphy, Kirsten Nørgaard, David O'Neal, Sean Oser, Tamara Oser, Eric Renard, Michael C Riddell, David Rodbard, Steven J Russell, Desmond A Schatz, Viral N Shah, Jennifer L Sherr, Gregg D Simonson, R Paul Wadwa, Candice Ward, Stuart A Weinzimer, Emma G Wilmot, Tadej Battelino.
Endocr Rev. 2023 Mar 4;44(2):254-280. doi: 10.1210/endrev/bnac022.
Feasibility and Preliminary Safety of Smartphone-Based Automated Insulin Delivery in Adolescents and Children With Type 1 Diabetes.
Sunil Deshpande, Stuart A Weinzimer, Kathryn Gibbons, Laura M Nally, Kate Weyman, Lori Carria, Melinda Zgorski, Lori M Laffel, Francis J Doyle, Eyal Dassau.
J Diabetes Sci Technol. 2024 Mar;18(2):363-371. doi: 10.1177/19322968221116384. Epub 2022 Aug 16.
Concept of the "Universal Slope": Toward Substantially Shorter Decentralized Insulin Immunoassays.
Eva Vargas, Eleonora M Aiello, Amira Ben Hassine, Victor Ruiz-Valdepeñas Montiel, Jordan E Pinsker, Mei Mei Church, Lori M Laffel, Francis J Doyle, Mary-Elizabeth Patti, Eyal Dassau, Joseph Wang.
Anal Chem. 2022 Jul 5;94(26):9217-9225. doi: 10.1021/acs.analchem.2c02178. Epub 2022 Jun 17.
Microneedle Aptamer-Based Sensors for Continuous, Real-Time Therapeutic Drug Monitoring.
Yao Wu, Farshad Tehrani, Hazhir Teymourian, John Mack, Alexander Shaver, Maria Reynoso, Jonathan Kavner, Nickey Huang, Allison Furmidge, Andrés Duvvuri, Yuhang Nie, Lori M Laffel, Francis J Doyle, Mary-Elizabeth Patti, Eyal Dassau, Joseph Wang, Netzahualcóyotl Arroyo-Currás.
Anal Chem. 2022 Jun 14;94(23):8335-8345. doi: 10.1021/acs.analchem.2c00829. Epub 2022 Jun 2.
Outpatient Randomized Crossover Comparison of Zone Model Predictive Control Automated Insulin Delivery with Weekly Data Driven Adaptation Versus Sensor-Augmented Pump: Results from the International Diabetes Closed-Loop Trial 4.
Jordan E Pinsker, Eyal Dassau, Sunil Deshpande, Dan Raghinaru, Bruce A Buckingham, Yogish C Kudva, Lori M Laffel, Carol J Levy, Mei Mei Church, Hannah Desrochers, Laya Ekhlaspour, Ravinder Jeet Kaur, Camilla Levister, Dawei Shi, John W Lum, Craig Kollman, Francis J Doyle, iDCL Trial Research Group.
Diabetes Technol Ther. 2022 Sep;24(9):635-642. doi: 10.1089/dia.2022.0084. Epub 2022 Jun 2.
Zone-MPC Automated Insulin Delivery Algorithm Tuned for Pregnancy Complicated by Type 1 Diabetes.
Basak Ozaslan, Sunil Deshpande, Francis J Doyle, Eyal Dassau.
Front Endocrinol (Lausanne). 2022 Mar 22;12:768639. doi: 10.3389/fendo.2021.768639. eCollection 2021.
A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings.
David C Klonoff, Jing Wang, David Rodbard, Michael A Kohn, Chengdong Li, Dorian Liepmann, David Kerr, David Ahn, Anne L Peters, Guillermo E Umpierrez, Jane Jeffrie Seley, Nicole Y Xu, Kevin T Nguyen, Gregg Simonson, Michael S D Agus, Mohammed E Al-Sofiani, Gustavo Armaiz-Pena, Timothy S Bailey, Ananda Basu, Tadej Battelino, Sewagegn Yeshiwas Bekele, Pierre-Yves Benhamou, B Wayne Bequette, Thomas Blevins, Marc D Breton, Jessica R Castle, James Geoffrey Chase, Kong Y Chen, Pratik Choudhary, Mark A Clements, Kelly L Close, Curtiss B Cook, Thomas Danne, Francis J Doyle, Angela Drincic, Kathleen M Dungan, Steven V Edelman, Niels Ejskjaer, Juan C Espinoza, G Alexander Fleming, Gregory P Forlenza, Guido Freckmann, Rodolfo J Galindo, Ana Maria Gomez, Hanna A Gutow, Lutz Heinemann, Irl B Hirsch, Thanh D Hoang, Roman Hovorka, Johan H Jendle, Linong Ji, Shashank R Joshi, Michael Joubert, Suneil K Koliwad, Rayhan A Lal, M Cecilia Lansang, Wei-An Andy Lee, Lalantha Leelarathna, Lawrence A Leiter, Marcus Lind, Michelle L Litchman, Julia K Mader, Katherine M Mahoney, Boris Mankovsky, Umesh Masharani, Nestoras N Mathioudakis, Alexander Mayorov, Jordan Messler, Joshua D Miller, Viswanathan Mohan, James H Nichols, Kirsten Nørgaard, David N O'Neal, Francisco J Pasquel, Athena Philis-Tsimikas, Thomas Pieber, Moshe Phillip, William H Polonsky, Rodica Pop-Busui, Gerry Rayman, Eun-Jung Rhee, Steven J Russell, Viral N Shah, Jennifer L Sherr, Koji Sode, Elias K Spanakis, Deborah J Wake, Kayo Waki, Amisha Wallia, Melissa E Weinberg, Howard Wolpert, Eugene E Wright, Mihail Zilbermint, Boris Kovatchev.
J Diabetes Sci Technol. 2023 Sep;17(5):1226-1242. doi: 10.1177/19322968221085273. Epub 2022 Mar 29.
Hypoglycemia in Prospective Multicenter Study of Pregnancies with Pre-Existing Type 1 Diabetes on Sensor-Augmented Pump Therapy: The LOIS-P Study.
Ravinder Jeet Kaur, Byron H Smith, Basak Ozaslan, Jordan E Pinsker, Mari Charisse Trinidad, Grenye O'Malley, Donna Desjardins, Kristin N Castorino, Camilla Levister, Corey Reid, Shelly McCrady-Spitzer, Selassie J Ogyaadu, Mei Mei Church, Molly Piper, Walter K Kremers, Barak Rosenn, Francis J Doyle, Eyal Dassau, Carol J Levy, Yogish C Kudva.
Diabetes Technol Ther. 2022 Aug;24(8):544-555. doi: 10.1089/dia.2021.0479.
Feasibility of Closed-Loop Insulin Delivery with a Pregnancy-Specific Zone Model Predictive Control Algorithm.
Basak Ozaslan, Carol J Levy, Yogish C Kudva, Jordan E Pinsker, Grenye O'Malley, Ravinder Jeet Kaur, Kristin Castorino, Camilla Levister, Mari Charisse Trinidad, Donna Desjardins, Mei Mei Church, Mitchell Plesser, Shelly McCrady-Spitzer, Selassie Ogyaadu, Kristen Nelson, Corey Reid, Sunil Deshpande, Walter K Kremers, Francis J Doyle, Barak Rosenn, Eyal Dassau.
Diabetes Technol Ther. 2022 Jul;24(7):471-480. doi: 10.1089/dia.2021.0521. Epub 2022 Apr 26.
Intraperitoneal Insulin Delivery: Evidence of a Physiological Route for Artificial Pancreas From Compartmental Modeling.
Jorge Lo Presti, Alfonso Galderisi, Francis J Doyle, Howard C Zisser, Eyal Dassau, Eric Renard, Chiara Toffanin, Claudio Cobelli.
J Diabetes Sci Technol. 2023 May;17(3):751-756. doi: 10.1177/19322968221076559. Epub 2022 Feb 10.
Clinical Evaluation of a Novel Insulin Immunosensor.
Eleonora M Aiello, Jordan E Pinsker, Eva Vargas, Hazhir Teymourian, Farshad Tehrani, Mei Mei Church, Lori M Laffel, Francis J Doyle, Mary-Elizabeth Patti, Joseph Wang, Eyal Dassau.
J Diabetes Sci Technol. 2023 Jul;17(4):1038-1048. doi: 10.1177/19322968221074406. Epub 2022 Feb 4.
Development of a Novel Insulin Sensor for Clinical Decision-Making.
Eva Vargas, Eleonora M Aiello, Jordan E Pinsker, Hazhir Teymourian, Farshad Tehrani, Mei Mei Church, Lori M Laffel, Francis J Doyle, Mary-Elizabeth Patti, Eyal Dassau, Joseph Wang.
J Diabetes Sci Technol. 2023 Jul;17(4):1029-1037. doi: 10.1177/19322968211071132. Epub 2022 Jan 19.
Serum brain-derived neurotrophic factor remains elevated after long term follow-up of combat veterans with chronic post-traumatic stress disorder.
Gwyneth W Y Wu, Owen M Wolkowitz, Victor I Reus, Jee In Kang, Mathea Elnar, Reuben Sarwal, Janine D Flory, Duna Abu-Amara, Rasha Hammamieh, Aarti Gautam, Francis J Doyle, Rachel Yehuda, Charles R Marmar, Marti Jett, Synthia H Mellon, SBPBC.
Psychoneuroendocrinology. 2021 Dec;134:105360. doi: 10.1016/j.psyneuen.2021.105360. Epub 2021 Jul 22.
Modeling the Influence of Chronic Sleep Restriction on Cortisol Circadian Rhythms, with Implications for Metabolic Disorders.
Rohit Rao, Pramod Somvanshi, Elizabeth B Klerman, Charles Marmar, Francis J Doyle.
Metabolites. 2021 Jul 27;11(8):483. doi: 10.3390/metabo11080483.
Review of Automated Insulin Delivery Systems for Individuals with Type 1 Diabetes: Tailored Solutions for Subpopulations.
Eleonora M Aiello, Sunil Deshpande, Basak Ozaslan, Kelilah L Wolkowicz, Eyal Dassau, Jordan E Pinsker, Francis J Doyle.
Curr Opin Biomed Eng. 2021 Sep;19:100312. doi: 10.1016/j.cobme.2021.100312. Epub 2021 Jun 18.
Longitudinal Observation of Insulin Use and Glucose Sensor Metrics in Pregnant Women with Type 1 Diabetes Using Continuous Glucose Monitors and Insulin Pumps: The LOIS-P Study.
Grenye O'Malley, Basak Ozaslan, Carol J Levy, Kristin Castorino, Donna Desjardins, Camilla Levister, Shelly McCrady-Spitzer, Mei Mei Church, Ravinder Jeet Kaur, Corey Reid, Walter K Kremers, Francis J Doyle, Mari Charisse Trinidad, Barak Rosenn, Jordan E Pinsker, Yogish C Kudva, Eyal Dassau.
Diabetes Technol Ther. 2021 Dec;23(12):807-817. doi: 10.1089/dia.2021.0112. Epub 2021 Aug 17.
A classification approach to estimating human circadian phase under circadian alignment from actigraphy and photometry data.
Lindsey S Brown, Melissa A St Hilaire, Andrew W McHill, Andrew J K Phillips, Laura K Barger, Akane Sano, Charles A Czeisler, Francis J Doyle, Elizabeth B Klerman.
J Pineal Res. 2021 Aug;71(1):e12745. doi: 10.1111/jpi.12745. Epub 2021 Jun 20.
A review of biomarkers in the context of type 1 diabetes: Biological sensing for enhanced glucose control.
Kelilah L Wolkowicz, Eleonora M Aiello, Eva Vargas, Hazhir Teymourian, Farshad Tehrani, Joseph Wang, Jordan E Pinsker, Francis J Doyle, Mary-Elizabeth Patti, Lori M Laffel, Eyal Dassau.
Bioeng Transl Med. 2020 Dec 9;6(2):e10201. doi: 10.1002/btm2.10201. eCollection 2021 May.
Utilization of machine learning for identifying symptom severity military-related PTSD subtypes and their biological correlates.
Carole E Siegel, Eugene M Laska, Ziqiang Lin, Mu Xu, Duna Abu-Amara, Michelle K Jeffers, Meng Qian, Nicholas Milton, Janine D Flory, Rasha Hammamieh, Bernie J Daigle, Aarti Gautam, Kelsey R Dean, Victor I Reus, Owen M Wolkowitz, Synthia H Mellon, Kerry J Ressler, Rachel Yehuda, Kai Wang, Leroy Hood, Francis J Doyle, Marti Jett, Charles R Marmar.
Transl Psychiatry. 2021 Apr 20;11(1):227. doi: 10.1038/s41398-021-01324-8.
Nonlinear Model Predictive Control For Circadian Entrainment Using Small-Molecule Pharmaceuticals.
John H Abel, Ankush Chakrabarty, Francis J Doyle.
IFAC Pap OnLine. 2017 Jul;50(1):9864-9870. doi: 10.1016/j.ifacol.2017.08.1596. Epub 2017 Oct 18.
Embedded Model Predictive Control for a Wearable Artificial Pancreas.
Ankush Chakrabarty, Elizabeth Healey, Dawei Shi, Stamatina Zavitsanou, Francis J Doyle, Eyal Dassau.
IEEE Trans Control Syst Technol. 2020 Nov;28(6):2600-2607. doi: 10.1109/tcst.2019.2939122. Epub 2019 Sep 18.
Compensating for Sensor Error in the Model Predictive Control of Circadian Clock Phase.
Lindsey S Brown, Elizabeth B Klerman, Francis J Doyle.
IEEE Control Syst Lett. 2019 Oct;3(4):853-858. doi: 10.1109/lcsys.2019.2919438. Epub 2019 May 28.
Machine Learning-Based Anomaly Detection Algorithms to Alert Patients Using Sensor Augmented Pump of Infusion Site Failures.
Lorenzo Meneghetti, Eyal Dassau, Francis J Doyle, Simone Del Favero.
J Diabetes Sci Technol. 2022 May;16(3):641-648. doi: 10.1177/1932296821997854. Epub 2021 Mar 9.
Epigenetic biotypes of post-traumatic stress disorder in war-zone exposed veteran and active duty males.
Ruoting Yang, Aarti Gautam, Derese Getnet, Bernie J Daigle, Stacy Miller, Burook Misganaw, Kelsey R Dean, Raina Kumar, Seid Muhie, Kai Wang, Inyoul Lee, Duna Abu-Amara, Janine D Flory, PTSD Systems Biology Consortium, Leroy Hood, Owen M Wolkowitz, Synthia H Mellon, Francis J Doyle, Rachel Yehuda, Charles R Marmar, Kerry J Ressler, Rasha Hammamieh, Marti Jett.
Mol Psychiatry. 2021 Aug;26(8):4300-4314. doi: 10.1038/s41380-020-00966-2. Epub 2020 Dec 18.
A dual-feedback loop model of the mammalian circadian clock for multi-input control of circadian phase.
Lindsey S Brown, Francis J Doyle.
PLoS Comput Biol. 2020 Nov 23;16(11):e1008459. doi: 10.1371/journal.pcbi.1008459. eCollection 2020 Nov.
Assessing Mealtime Macronutrient Content: Patient Perceptions Versus Expert Analyses via a Novel Phone App.
Melanie B Gillingham, Zoey Li, Roy W Beck, Peter Calhoun, Jessica R Castle, Mark Clements, Eyal Dassau, Francis J Doyle, Robin L Gal, Peter Jacobs, Susana R Patton, Michael R Rickels, Michael Riddell, Corby K Martin.
Diabetes Technol Ther. 2021 Feb;23(2):85-94. doi: 10.1089/dia.2020.0357. Epub 2020 Sep 29.
Use of the Interoperable Artificial Pancreas System for Type 1 Diabetes Management During Psychological Stress.
Jordan E Pinsker, Sunil Deshpande, Shelly McCrady-Spitzer, Mei Mei Church, Ravinder Jeet Kaur, Jimena Perez, Donna Desjardins, Molly Piper, Corey Reid, Francis J Doyle, Yogish C Kudva, Eyal Dassau.
J Diabetes Sci Technol. 2021 Jan;15(1):184-185. doi: 10.1177/1932296820948566. Epub 2020 Aug 12.
Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony.
Yongli Shan, John H Abel, Yan Li, Mariko Izumo, Kimberly H Cox, Byeongha Jeong, Seung-Hee Yoo, David P Olson, Francis J Doyle, Joseph S Takahashi.
Neuron. 2020 Oct 14;108(1):164-179.e7. doi: 10.1016/j.neuron.2020.07.012. Epub 2020 Aug 7.
Correction: A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD.
Ruoting Yang, Gwyneth W Y Wu, Josine E Verhoeven, Aarti Gautam, Victor I Reus, Jee In Kang, Janine D Flory, Duna Abu-Amara, PTSD Systems Biology Consortium, Leroy Hood, Francis J Doyle, Rachel Yehuda, Charles R Marmar, Marti Jett, Rasha Hammamieh, Synthia H Mellon, Owen M Wolkowitz.
Mol Psychiatry. 2021 Sep;26(9):5010. doi: 10.1038/s41380-020-0837-y.
Pre-deployment risk factors for PTSD in active-duty personnel deployed to Afghanistan: a machine-learning approach for analyzing multivariate predictors.
Katharina Schultebraucks, Meng Qian, Duna Abu-Amara, Kelsey Dean, Eugene Laska, Carole Siegel, Aarti Gautam, Guia Guffanti, Rasha Hammamieh, Burook Misganaw, Synthia H Mellon, Owen M Wolkowitz, Esther M Blessing, Amit Etkin, Kerry J Ressler, Francis J Doyle, Marti Jett, Charles R Marmar.
Mol Psychiatry. 2021 Sep;26(9):5011-5022. doi: 10.1038/s41380-020-0789-2. Epub 2020 Jun 2.
Glycemic Outcomes of Use of CLC Versus PLGS in Type 1 Diabetes: A Randomized Controlled Trial.
Sue A Brown, Roy W Beck, Dan Raghinaru, Bruce A Buckingham, Lori M Laffel, R Paul Wadwa, Yogish C Kudva, Carol J Levy, Jordan E Pinsker, Eyal Dassau, Francis J Doyle, Louise Ambler-Osborn, Stacey M Anderson, Mei Mei Church, Laya Ekhlaspour, Gregory P Forlenza, Camilla Levister, Vinaya Simha, Marc D Breton, Craig Kollman, John W Lum, Boris P Kovatchev, iDCL Trial Research Group.
Diabetes Care. 2020 Aug;43(8):1822-1828. doi: 10.2337/dc20-0124. Epub 2020 May 29.
Effect of Combat Exposure and Posttraumatic Stress Disorder on Telomere Length and Amygdala Volume.
Jee In Kang, Susanne G Mueller, Gwyneth W Y Wu, Jue Lin, Peter Ng, Rachel Yehuda, Janine D Flory, Duna Abu-Amara, Victor I Reus, Aarti Gautam, PTSD Systems Biology Consortium, Rasha Hammamieh, Francis J Doyle, Marti Jett, Charles R Marmar, Synthia H Mellon, Owen M Wolkowitz.
Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Jul;5(7):678-687. doi: 10.1016/j.bpsc.2020.03.007. Epub 2020 Mar 31.
A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD.
Ruoting Yang, Gwyneth W Y Wu, Josine E Verhoeven, Aarti Gautam, Victor I Reus, Jee In Kang, Janine D Flory, Duna Abu-Amara, PTSD Systems Biology Consortium, Leroy Hood, Francis J Doyle, Rachel Yehuda, Charles R Marmar, Marti Jett, Rasha Hammamieh, Synthia H Mellon, Owen M Wolkowitz.
Mol Psychiatry. 2021 Sep;26(9):4999-5009. doi: 10.1038/s41380-020-0755-z. Epub 2020 May 7.
Role of enhanced glucocorticoid receptor sensitivity in inflammation in PTSD: insights from computational model for circadian-neuroendocrine-immune interactions.
Pramod R Somvanshi, Synthia H Mellon, Rachel Yehuda, Janine D Flory, Iouri Makotkine, Linda Bierer, Charles Marmar, Marti Jett, Francis J Doyle.
Am J Physiol Endocrinol Metab. 2020 Jul 1;319(1):E48-E66. doi: 10.1152/ajpendo.00398.2019. Epub 2020 Apr 21.
Erratum. Randomized Controlled Trial of Mobile Closed-Loop Control. Diabetes Care 2020;43:607-615.
Boris Kovatchev, Stacey M Anderson, Dan Raghinaru, Yogish C Kudva, Lori M Laffel, Carol Levy, Jordan E Pinsker, R Paul Wadwa, Bruce Buckingham, Francis J Doyle, Sue A Brown, Mei Mei Church, Vikash Dadlani, Eyal Dassau, Laya Ekhlaspour, Gregory P Forlenza, Elvira Isganaitis, David W Lam, John Lum, Roy W Beck, iDCL Study Group.
Diabetes Care. 2020 Jun;43(6):1366. doi: 10.2337/dc20-er06. Epub 2020 Apr 3.
Novel Pharmacological Targets for Combat PTSD-Metabolism, Inflammation, The Gut Microbiome, and Mitochondrial Dysfunction.
F Saverio Bersani, Synthia H Mellon, Daniel Lindqvist, Jee In Kang, Ryan Rampersaud, Pramod Rajaram Somvanshi, Francis J Doyle, Rasha Hammamieh, Marti Jett, Rachel Yehuda, Charles R Marmar, Owen M Wolkowitz.
Mil Med. 2020 Jan 7;185(Suppl 1):311-318. doi: 10.1093/milmed/usz260.
Randomized Controlled Trial of Mobile Closed-Loop Control.
Boris Kovatchev, Stacey M Anderson, Dan Raghinaru, Yogish C Kudva, Lori M Laffel, Carol Levy, Jordan E Pinsker, R Paul Wadwa, Bruce Buckingham, Francis J Doyle, Sue A Brown, Mei Mei Church, Vikash Dadlani, Eyal Dassau, Laya Ekhlaspour, Gregory P Forlenza, Elvira Isganaitis, David W Lam, John Lum, Roy W Beck, iDCL Study Group.
Diabetes Care. 2020 Mar;43(3):607-615. doi: 10.2337/dc19-1310. Epub 2020 Jan 14.
A Randomized, Placebo-Controlled Double-Blind Trial of a Closed-Loop Glucagon System for Postbariatric Hypoglycemia.
Christopher M Mulla, Stamatina Zavitsanou, Alejandro Jose Laguna Sanz, David Pober, Lauren Richardson, Pamela Walcott, Ipsa Arora, Brett Newswanger, Martin J Cummins, Steve J Prestrelski, Francis J Doyle, Eyal Dassau, Mary Elizabeth Patti.
J Clin Endocrinol Metab. 2020 Apr 1;105(4):e1260-71. doi: 10.1210/clinem/dgz197.
Pharmaceutical-based entrainment of circadian phase via nonlinear model predictive control.
John H Abel, Ankush Chakrabarty, Elizabeth B Klerman, Francis J Doyle.
Automatica (Oxf). 2019 Feb;100:336-348. doi: 10.1016/j.automatica.2018.11.012. Epub 2018 Dec 10.
Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes.
Sue A Brown, Boris P Kovatchev, Dan Raghinaru, John W Lum, Bruce A Buckingham, Yogish C Kudva, Lori M Laffel, Carol J Levy, Jordan E Pinsker, R Paul Wadwa, Eyal Dassau, Francis J Doyle, Stacey M Anderson, Mei Mei Church, Vikash Dadlani, Laya Ekhlaspour, Gregory P Forlenza, Elvira Isganaitis, David W Lam, Craig Kollman, Roy W Beck, iDCL Trial Research Group.
N Engl J Med. 2019 Oct 31;381(18):1707-1717. doi: 10.1056/NEJMoa1907863. Epub 2019 Oct 16.
Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder.
Kelsey R Dean, Rasha Hammamieh, Synthia H Mellon, Duna Abu-Amara, Janine D Flory, Guia Guffanti, Kai Wang, Bernie J Daigle, Aarti Gautam, Inyoul Lee, Ruoting Yang, Lynn M Almli, F Saverio Bersani, Nabarun Chakraborty, Duncan Donohue, Kimberly Kerley, Taek-Kyun Kim, Eugene Laska, Min Young Lee, Daniel Lindqvist, Adriana Lori, Liangqun Lu, Burook Misganaw, Seid Muhie, Jennifer Newman, Nathan D Price, Shizhen Qin, Victor I Reus, Carole Siegel, Pramod R Somvanshi, Gunjan S Thakur, Yong Zhou, PTSD Systems Biology Consortium, Leroy Hood, Kerry J Ressler, Owen M Wolkowitz, Rachel Yehuda, Marti Jett, Francis J Doyle, Charles Marmar.
Mol Psychiatry. 2020 Dec;25(12):3337-3349. doi: 10.1038/s41380-019-0496-z. Epub 2019 Sep 10.
Mechanistic inferences on metabolic dysfunction in posttraumatic stress disorder from an integrated model and multiomic analysis: role of glucocorticoid receptor sensitivity.
Pramod R Somvanshi, Synthia H Mellon, Janine D Flory, Duna Abu-Amara, PTSD Systems Biology Consortium;, Owen M Wolkowitz, Rachel Yehuda, Marti Jett, Leroy Hood, Charles Marmar, Francis J Doyle.
Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E879-E898. doi: 10.1152/ajpendo.00065.2019. Epub 2019 Jul 19.
Reply to Furlan et al.: The role of SIRT1 in cell autonomous clock function.
Panagiota T Foteinou, Anand Venkataraman, Lauren J Francey, Ron C Anafi, John B Hogenesch, Francis J Doyle.
Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13173. doi: 10.1073/pnas.1907923116. Epub 2019 Jun 25.
A New Animal Model of Insulin-Glucose Dynamics in the Intraperitoneal Space Enhances Closed-Loop Control Performance.
Ankush Chakrabarty, Justin M Gregory, L Merkle Moore, Philip E Williams, Ben Farmer, Alan D Cherrington, Peter Lord, Brian Shelton, Don Cohen, Howard C Zisser, Francis J Doyle, Eyal Dassau.
J Process Control. 2019 Apr;76:62-73. doi: 10.1016/j.jprocont.2019.01.002. Epub 2019 Feb 23.
Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range.
Tadej Battelino, Thomas Danne, Richard M Bergenstal, Stephanie A Amiel, Roy Beck, Torben Biester, Emanuele Bosi, Bruce A Buckingham, William T Cefalu, Kelly L Close, Claudio Cobelli, Eyal Dassau, J Hans DeVries, Kim C Donaghue, Klemen Dovc, Francis J Doyle, Satish Garg, George Grunberger, Simon Heller, Lutz Heinemann, Irl B Hirsch, Roman Hovorka, Weiping Jia, Olga Kordonouri, Boris Kovatchev, Aaron Kowalski, Lori Laffel, Brian Levine, Alexander Mayorov, Chantal Mathieu, Helen R Murphy, Revital Nimri, Kirsten Nørgaard, Christopher G Parkin, Eric Renard, David Rodbard, Banshi Saboo, Desmond Schatz, Keaton Stoner, Tatsuiko Urakami, Stuart A Weinzimer, Moshe Phillip.
Diabetes Care. 2019 Aug;42(8):1593-1603. doi: 10.2337/dci19-0028. Epub 2019 Jun 8.
Polygenic risk associated with post-traumatic stress disorder onset and severity.
Burook Misganaw, Guia Guffanti, Adriana Lori, Duna Abu-Amara, Janine D Flory, SBPBC, Susanne Mueller, Rachel Yehuda, Marti Jett, Charles R Marmar, Kerry J Ressler, Francis J Doyle.
Transl Psychiatry. 2019 Jun 7;9(1):165. doi: 10.1038/s41398-019-0497-3.
Metabolomic analysis of male combat veterans with post traumatic stress disorder.
Synthia H Mellon, F Saverio Bersani, Daniel Lindqvist, Rasha Hammamieh, Duncan Donohue, Kelsey Dean, Marti Jett, Rachel Yehuda, Janine Flory, Victor I Reus, Linda M Bierer, Iouri Makotkine, Duna Abu Amara, Clare Henn Haase, Michelle Coy, Francis J Doyle, Charles Marmar, Owen M Wolkowitz.
PLoS One. 2019 Mar 18;14(3):e0213839. doi: 10.1371/journal.pone.0213839. eCollection 2019.
Multivariate learning framework for long-term adaptation in the artificial pancreas.
Dawei Shi, Eyal Dassau, Francis J Doyle.
Bioeng Transl Med. 2018 Nov 12;4(1):61-74. doi: 10.1002/btm2.10119. eCollection 2019 Jan.
The International Diabetes Closed-Loop Study: Testing Artificial Pancreas Component Interoperability.
Stacey M Anderson, Eyal Dassau, Dan Raghinaru, John Lum, Sue A Brown, Jordan E Pinsker, Mei Mei Church, Carol Levy, David Lam, Yogish C Kudva, Bruce Buckingham, Gregory P Forlenza, R Paul Wadwa, Lori Laffel, Francis J Doyle, J Hans DeVries, Eric Renard, Claudio Cobelli, Federico Boscari, Simone Del Favero, Boris P Kovatchev.
Diabetes Technol Ther. 2019 Feb;21(2):73-80. doi: 10.1089/dia.2018.0308. Epub 2019 Jan 16.
Design and Clinical Evaluation of the Interoperable Artificial Pancreas System (iAPS) Smartphone App: Interoperable Components with Modular Design for Progressive Artificial Pancreas Research and Development.
Sunil Deshpande, Jordan E Pinsker, Stamatina Zavitsanou, Dawei Shi, Randy Tompot, Mei Mei Church, Camille Andre, Francis J Doyle, Eyal Dassau.
Diabetes Technol Ther. 2019 Jan;21(1):35-43. doi: 10.1089/dia.2018.0278. Epub 2018 Dec 14.
Computational and experimental insights into the circadian effects of SIRT1.
Panagiota T Foteinou, Anand Venkataraman, Lauren J Francey, Ron C Anafi, John B Hogenesch, Francis J Doyle.
Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11643-11648. doi: 10.1073/pnas.1803410115. Epub 2018 Oct 22.
Chemical hazard prediction and hypothesis testing using quantitative adverse outcome pathways.
Edward J Perkins, Kalyan Gayen, Jason E Shoemaker, Philipp Antczak, Lyle Burgoon, Francesco Falciani, Steve Gutsell, Geoff Hodges, Aude Kienzler, Dries Knapen, Mary McBride, Catherine Willett, Francis J Doyle, Natàlia Garcia-Reyero.
ALTEX. 2019;36(1):91-102. doi: 10.14573/altex.1808241. Epub 2018 Oct 16.
Adaptive Zone Model Predictive Control of Artificial Pancreas Based on Glucose- and Velocity-Dependent Control Penalties.
Dawei Shi, Eyal Dassau, Francis J Doyle.
IEEE Trans Biomed Eng. 2019 Apr;66(4):1045-1054. doi: 10.1109/TBME.2018.2866392. Epub 2018 Aug 21.
Velocity-weighting & velocity-penalty MPC of an artificial pancreas: Improved safety & performance.
Ravi Gondhalekar, Eyal Dassau, Francis J Doyle.
Automatica (Oxf). 2018 May;91:105-117. doi: 10.1016/j.automatica.2018.01.025. Epub 2018 Mar 20.
Entrainment of Circadian Rhythms Depends on Firing Rates and Neuropeptide Release of VIP SCN Neurons.
Cristina Mazuski, John H Abel, Samantha P Chen, Tracey O Hermanstyne, Jeff R Jones, Tatiana Simon, Francis J Doyle, Erik D Herzog.
Neuron. 2018 Aug 8;99(3):555-563.e5. doi: 10.1016/j.neuron.2018.06.029. Epub 2018 Jul 12.
Extremum Seeking Control for Personalized Zone Adaptation in Model Predictive Control for Type 1 Diabetes.
Zhixing Cao, Ravi Gondhalekar, Eyal Dassau, Francis J Doyle.
IEEE Trans Biomed Eng. 2018 Aug;65(8):1859-1870. doi: 10.1109/TBME.2017.2783238. Epub 2017 Dec 13.
Evaluation of an Artificial Pancreas with Enhanced Model Predictive Control and a Glucose Prediction Trust Index with Unannounced Exercise.
Jordan E Pinsker, Alejandro J Laguna Sanz, Joon Bok Lee, Mei Mei Church, Camille Andre, Laura E Lindsey, Francis J Doyle, Eyal Dassau.
Diabetes Technol Ther. 2018 Jul;20(7):455-464. doi: 10.1089/dia.2018.0031.
Body Mass Index Effect on Differing Responses to Psychological Stress in Blood Glucose Dynamics in Patients With Type 1 Diabetes.
Basak Ozaslan, Stephen D Patek, Jesse H Grabman, Jaclyn A Shepard, Eyal Dassau, Marc D Breton, Yogish C Kudva, Sue A Brown, Ananda Basu, Jordan E Pinsker, Francis J Doyle, Linda Gonder-Frederick.
J Diabetes Sci Technol. 2018 May;12(3):657-664. doi: 10.1177/1932296818758103. Epub 2018 Feb 8.
Real-Time Detection of Infusion Site Failures in a Closed-Loop Artificial Pancreas.
Daniel P Howsmon, Nihat Baysal, Bruce A Buckingham, Gregory P Forlenza, Trang T Ly, David M Maahs, Tatiana Marcal, Lindsey Towers, Eric Mauritzen, Sunil Deshpande, Lauren M Huyett, Jordan E Pinsker, Ravi Gondhalekar, Francis J Doyle, Eyal Dassau, Juergen Hahn, B Wayne Bequette.
J Diabetes Sci Technol. 2018 May;12(3):599-607. doi: 10.1177/1932296818755173. Epub 2018 Feb 1.
Design and Clinical Evaluation of a Novel Low-Glucose Prediction Algorithm with Mini-Dose Stable Glucagon Delivery in Post-Bariatric Hypoglycemia.
Alejandro J Laguna Sanz, Christopher M Mulla, Kristen M Fowler, Emilie Cloutier, Allison B Goldfine, Brett Newswanger, Martin Cummins, Sunil Deshpande, Steven J Prestrelski, Poul Strange, Howard Zisser, Francis J Doyle, Eyal Dassau, Mary-Elizabeth Patti.
Diabetes Technol Ther. 2018 Feb;20(2):127-139. doi: 10.1089/dia.2017.0298.
International Consensus on Use of Continuous Glucose Monitoring.
Thomas Danne, Revital Nimri, Tadej Battelino, Richard M Bergenstal, Kelly L Close, J Hans DeVries, Satish Garg, Lutz Heinemann, Irl Hirsch, Stephanie A Amiel, Roy Beck, Emanuele Bosi, Bruce Buckingham, Claudio Cobelli, Eyal Dassau, Francis J Doyle, Simon Heller, Roman Hovorka, Weiping Jia, Tim Jones, Olga Kordonouri, Boris Kovatchev, Aaron Kowalski, Lori Laffel, David Maahs, Helen R Murphy, Kirsten Nørgaard, Christopher G Parkin, Eric Renard, Banshi Saboo, Mauro Scharf, William V Tamborlane, Stuart A Weinzimer, Moshe Phillip.
Diabetes Care. 2017 Dec;40(12):1631-1640. doi: 10.2337/dc17-1600.
Guidelines for Genome-Scale Analysis of Biological Rhythms.
Michael E Hughes, Katherine C Abruzzi, Ravi Allada, Ron Anafi, Alaaddin Bulak Arpat, Gad Asher, Pierre Baldi, Charissa de Bekker, Deborah Bell-Pedersen, Justin Blau, Steve Brown, M Fernanda Ceriani, Zheng Chen, Joanna C Chiu, Juergen Cox, Alexander M Crowell, Jason P DeBruyne, Derk-Jan Dijk, Luciano DiTacchio, Francis J Doyle, Giles E Duffield, Jay C Dunlap, Kristin Eckel-Mahan, Karyn A Esser, Garret A FitzGerald, Daniel B Forger, Lauren J Francey, Ying-Hui Fu, Frédéric Gachon, David Gatfield, Paul de Goede, Susan S Golden, Carla Green, John Harer, Stacey Harmer, Jeff Haspel, Michael H Hastings, Hanspeter Herzel, Erik D Herzog, Christy Hoffmann, Christian Hong, Jacob J Hughey, Jennifer M Hurley, Horacio O de la Iglesia, Carl Johnson, Steve A Kay, Nobuya Koike, Karl Kornacker, Achim Kramer, Katja Lamia, Tanya Leise, Scott A Lewis, Jiajia Li, Xiaodong Li, Andrew C Liu, Jennifer J Loros, Tami A Martino, Jerome S Menet, Martha Merrow, Andrew J Millar, Todd Mockler, Felix Naef, Emi Nagoshi, Michael N Nitabach, Maria Olmedo, Dmitri A Nusinow, Louis J Ptáček, David Rand, Akhilesh B Reddy, Maria S Robles, Till Roenneberg, Michael Rosbash, Marc D Ruben, Samuel S C Rund, Aziz Sancar, Paolo Sassone-Corsi, Amita Sehgal, Scott Sherrill-Mix, Debra J Skene, Kai-Florian Storch, Joseph S Takahashi, Hiroki R Ueda, Han Wang, Charles Weitz, Pål O Westermark, Herman Wijnen, Ying Xu, Gang Wu, Seung-Hee Yoo, Michael Young, Eric Erquan Zhang, Tomasz Zielinski, John B Hogenesch.
J Biol Rhythms. 2017 Oct;32(5):380-393. doi: 10.1177/0748730417728663. Epub 2017 Nov 3.
Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus.
Vania Carmona-Alcocer, John H Abel, Tao C Sun, Linda R Petzold, Francis J Doyle, Carrie L Simms, Erik D Herzog.
J Neurosci. 2018 Feb 7;38(6):1326-1334. doi: 10.1523/JNEUROSCI.2006-17.2017. Epub 2017 Oct 20.
A Personalized Week-to-Week Updating Algorithm to Improve Continuous Glucose Monitoring Performance.
Stamatina Zavitsanou, Joon Bok Lee, Jordan E Pinsker, Mei Mei Church, Francis J Doyle, Eyal Dassau.
J Diabetes Sci Technol. 2017 Nov;11(6):1070-1079. doi: 10.1177/1932296817734367. Epub 2017 Oct 16.
Twelve-Week 24/7 Ambulatory Artificial Pancreas With Weekly Adaptation of Insulin Delivery Settings: Effect on Hemoglobin A<sub>1c</sub> and Hypoglycemia.
Eyal Dassau, Jordan E Pinsker, Yogish C Kudva, Sue A Brown, Ravi Gondhalekar, Chiara Dalla Man, Steve Patek, Michele Schiavon, Vikash Dadlani, Isuru Dasanayake, Mei Mei Church, Rickey E Carter, Wendy C Bevier, Lauren M Huyett, Jonathan Hughes, Stacey Anderson, Dayu Lv, Elaine Schertz, Emma Emory, Shelly K McCrady-Spitzer, Tyler Jean, Paige K Bradley, Ling Hinshaw, Alejandro J Laguna Sanz, Ananda Basu, Boris Kovatchev, Claudio Cobelli, Francis J Doyle.
Diabetes Care. 2017 Dec;40(12):1719-1726. doi: 10.2337/dc17-1188. Epub 2017 Oct 13.
Erratum. Application of Zone Model Predictive Control Artificial Pancreas During Extended Use of Infusion Set and Sensor: A Randomized Crossover-Controlled Home-Use Trial. Diabetes Care 2017;40:1096-1102.
Gregory P Forlenza, Sunil Deshpande, Trang T Ly, Daniel P Howsmon, Faye Cameron, Nihat Baysal, Eric Mauritzen, Tatiana Marcal, Lindsey Towers, B Wayne Bequette, Lauren M Huyett, Jordan E Pinsker, Ravi Gondhalekar, Francis J Doyle, David M Maahs, Bruce A Buckingham, Eyal Dassau.
Diabetes Care. 2017 Nov;40(11):1606. doi: 10.2337/dc17-er11a. Epub 2017 Sep 8.
An Enhanced Model Predictive Control for the Artificial Pancreas Using a Confidence Index Based on Residual Analysis of Past Predictions.
Alejandro J Laguna Sanz, Francis J Doyle, Eyal Dassau.
J Diabetes Sci Technol. 2017 May;11(3):537-544. doi: 10.1177/1932296816680632. Epub 2016 Dec 1.
Application of Zone Model Predictive Control Artificial Pancreas During Extended Use of Infusion Set and Sensor: A Randomized Crossover-Controlled Home-Use Trial.
Gregory P Forlenza, Sunil Deshpande, Trang T Ly, Daniel P Howsmon, Faye Cameron, Nihat Baysal, Eric Mauritzen, Tatiana Marcal, Lindsey Towers, B Wayne Bequette, Lauren M Huyett, Jordan E Pinsker, Ravi Gondhalekar, Francis J Doyle, David M Maahs, Bruce A Buckingham, Eyal Dassau.
Diabetes Care. 2017 Aug;40(8):1096-1102. doi: 10.2337/dc17-0500. Epub 2017 Jun 5.
Event-Triggered Model Predictive Control for Embedded Artificial Pancreas Systems.
Ankush Chakrabarty, Stamatina Zavitsanou, Francis J Doyle, Eyal Dassau.
IEEE Trans Biomed Eng. 2018 Mar;65(3):575-586. doi: 10.1109/TBME.2017.2707344. Epub 2017 May 23.
A systems theoretic approach to analysis and control of mammalian circadian dynamics.
John H Abel, Francis J Doyle.
Chem Eng Res Des. 2016 Dec;116:48-60. doi: 10.1016/j.cherd.2016.09.033. Epub 2016 Oct 8.
Intraperitoneal insulin delivery provides superior glycaemic regulation to subcutaneous insulin delivery in model predictive control-based fully-automated artificial pancreas in patients with type 1 diabetes: a pilot study.
Eyal Dassau, Eric Renard, Jérôme Place, Anne Farret, Marie-José Pelletier, Justin Lee, Lauren M Huyett, Ankush Chakrabarty, Francis J Doyle, Howard C Zisser.
Diabetes Obes Metab. 2017 Dec;19(12):1698-1705. doi: 10.1111/dom.12999. Epub 2017 Jul 6.
Outpatient Closed-Loop Control with Unannounced Moderate Exercise in Adolescents Using Zone Model Predictive Control.
Lauren M Huyett, Trang T Ly, Gregory P Forlenza, Suzette Reuschel-DiVirgilio, Laurel H Messer, R Paul Wadwa, Ravi Gondhalekar, Francis J Doyle, Jordan E Pinsker, David M Maahs, Bruce A Buckingham, Eyal Dassau.
Diabetes Technol Ther. 2017 Jun;19(6):331-339. doi: 10.1089/dia.2016.0399. Epub 2017 May 1.
