Mar 10, 2014 - Group hike
A fun hike up to 3 pools
Mar 04, 2014 - UCSB’s Newest Research Hub
After several years of insufficient state funding, the effort toward a new bioengineering building on campus is back on track - See more at: http://www.news.ucsb.edu/2014/013992/ucsb%E2%80%99s-newest-research-hub#sthash.1WxC8cxE.dpuf
Jan 31, 2014 - Congratulations to Maria and Felipe on their new baby!
The Doyle group welcomes its newest member, Mariana! Born January 22nd, 2014.
Full size image
We wish Maria and Felipe the very best of luck with their new family.
Jan 28, 2014 - Resetting the Metabolic Clock
See a press release covering our recent publication, Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock:
UC Santa Barbara researchers’ new insight into mammalian circadian rhythms could lead to therapies for certain metabolic disorders like obesity and diabetes - See more at: http://www.news.ucsb.edu/2014/013919/resetting-metabolic-clock#sthash.kbLzwK6r.dpuf
Jan 23, 2014 - A Pancreas in a Box
The artificial pancreas project was recently highlighted in a Science News Focus, http://dx.doi.org/10.1126/science.343.6167.133
Pancreas_in_a_Box_Science_2014
Image Credit: ROMAN HOVORKA/UNIVERSITY OF CAMBRIDGE METABOLIC RESEARCH LABORATORIES
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Jan 10, 2014 - PTSD Research highlighted in Daily Nexus
Dec 09, 2013 - Army renews ICB funding
Army renews bio-inspired engineering and science research center at UC Santa Barbara with $48 million. Read more
Nov 26, 2013 - Professor Roger W.H Sargent Lecture
Nov 07, 2013 - Developing diagnostic tools for PTSD
A recent press release highlights our groups work in finding biomarkers of post-traumatic stress disorder (PTSD) in order to improve diagnosis and therapy:
http://dev.news.ucsb.edu/2013/013683/serving-those-who-have-served
Oct 29, 2013 - VIP Treatment for Jet Lag
A number of news articles were recently published on the results of collaborative work concerning synchrony of mammalian circadian rhythms:
- http://www.sciencecodex.com/
vip_treatment_for_jet_lag- 121910 - http://vr-zone.com/articles/
quick-natural-cure-jet-lag- possible/61944.html?utm_ source=rss&utm_medium=rss&utm_ campaign=quick-natural-cure- jet-lag-possible - http://www.telegraph.co.uk/
science/science-news/10409645/ Brain-chemical-helps-beat-jet- lag.html - http://www.healthline.com/
health-news/outdoor-a-shot-of- vip-could-treat-jet-lag-102813 - http://www.dailymail.co.uk/
health/article-2478431/The- jet-lag-jab-help-night-shift- workers-fix-body-clock.html
Oct 16, 2013 - Cutting Edge Biomedical Research in Your Own Backyard
This talk discusses the Artificial Pancreas System, focusing on the technical aspects of the system and the clinical research to date. It includes information on the challenges that such a complex system presents; the adaptive, non-linear control algorithm used to address these challenges and what the system can do to revolutionize diabetes care for patients with insulin-dependent diabetes.
Sep 24, 2013 - Ultra-Rapid-Acting Inhaled Insulin Trial Funded By JDRF
JDRF, Sansum Diabetes Research Institute, and the College of Engineering at University of California, Santa Barbara (UCSB) are pleased to announce the first successful clinical research trial using the artificial pancreas in conjunction with ultra-rapid-acting inhaled insulin.
This represents a groundbreaking potential advancement in the treatment of type 1 diabetes (T1D). It establishes that the disease can be managed through a unified automated process that delivers precise amounts of insulin around the clock, based on real-time glucose measurements without the need for patient intervention, and is further enhanced and fine-tuned by the swift delivery of ultra-rapid-acting inhaled insulin during mealtimes. The artificial pancreas and inhaled insulin system work together to replicate the normal, healthy function of the human pancreas. Sansum Diabetes is the only site testing ultra-rapid-acting inhaled insulin in combination with the artificial pancreas. Read more ...
Sep 19, 2013 - Defeating Diabetes with Technology
A recent news article in the Santa Barbara Independent highlights the potential benefits of our artificial pancreas system
http://www.independent.com/news/2013/sep/19/defeating-diabetes-technology/
Aug 26, 2013 - Congratulations to Dr. Rebecca Harvey
Congratulations to Rebecca Harvey, who successfully defended her PhD thesis!
Dec 12, 2012 - UCSB Researchers Perform Pioneering Research on Type 2 Diabetes
A press release covering our new article in Plos One: Read More
Original Article:
Luni C, Marth JD, Doyle FJ III (2012) Computational Modeling of Glucose Transport in Pancreatic β-Cells Identifies Metabolic Thresholds and Therapeutic Targets in Diabetes. PLoS ONE 7(12): e53130. doi:10.1371/journal.pone.0053130
Oct 23, 2012 - Glucose Monitoring through Meal Detection
A study looked at using continuous glucose monitoring to detect a meal. Eyal Dassau, PHD, of the University of California, Santa Barbara, said the ability to use a meal detection algorithm has safety and quality-of-life implications, particularly in children and adolescents, which is why the Juvenile Diabetes Research Foundation provided financial support for the study.
Adolescents often forget to bolus before eating, which results in very high blood glucose levels a couple of hours after a meal, which is something we'd like to avoid," Dr. Dassau said.
The study he presented looked at whether glucose rate-of-change data from a continuous glucose monitor could detect a meal. Dr. Dassau said the results indicated that the use of meal detection algorithm will trigger a model for predictive control of insulin dosing during a meal before there has been a major elevation in blood glucose levels. More...
Oct 19, 2012 - Smart Embedded Devices: Here They Come
A recent news article was published covering advances in the group on model predictive control (MPC)
Smart Embedded Devices: Here They Come
Jul 15, 2012 - Biological Clock Chemical Offers New Way to Treat Diabetes
A press release for a recent paper published in collaboration with researchers from UCSD.
Read More
Full Citation:
T. Hirota, J. W. Lee, P. C. St. John, M. Sawa, K. Iwaisako, T. Noguchi, P. Y. Pongsawakul, T. Sonntag, D. K. Welsh, D. a Brenner, F. J. Doyle, P. G. Schultz, and S. a Kay, “Identification of Small Molecule Activators of Cryptochrome.,” Science, vol. 337, no. 6098, pp. 1094–1097, Jul. 2012.
Jul 12, 2012 - Trial of artificial pancreas gives diabetes patients a break
Trial of artificial pancreas gives diabetes patients a break

